Engineering bacteria for enhanced polyhydroxyalkanoates (PHA) biosynthesis
نویسندگان
چکیده
منابع مشابه
Engineering bacteria for enhanced polyhydroxyalkanoates (PHA) biosynthesis
Polyhydroxyalkanoates (PHA) have been produced by some bacteria as bioplastics for many years. Yet their commercialization is still on the way. A few issues are related to the difficulty of PHA commercialization: namely, high cost and instabilities on molecular weights (Mw) and structures, thus instability on thermo-mechanical properties. The high cost is the result of complicated bioprocessing...
متن کاملSynthetic biology of microbes synthesizing polyhydroxyalkanoates (PHA)
Microbial polyhydroxyalkanoates (PHA) have been produced as bioplastics for various purposes. Under the support of China National Basic Research 973 Project, we developed synthetic biology methods to diversify the PHA structures into homo-, random, block polymers with improved properties to better meet various application requirements. At the same time, various pathways were assembled to produc...
متن کاملEngineering Halomonas species TD01 for enhanced polyhydroxyalkanoates synthesis via CRISPRi
BACKGROUND Clustered regularly interspaced short palindromic repeats interference (CRISPRi) has provided an efficient approach for targeted gene inhibition. A non-model microorganism Halomonas species TD01 has been developed as a promising industrial producer of polyhydroxyalkanoates (PHA), a family of biodegradable polyesters accumulated by bacteria as a carbon and energy reserve compound. A c...
متن کاملA microbial polyhydroxyalkanoates (PHA) based bio- and materials industry.
Biopolyesters polyhydroxyalkanoates (PHA) produced by many bacteria have been investigated by microbiologists, molecular biologists, biochemists, chemical engineers, chemists, polymer experts and medical researchers. PHA applications as bioplastics, fine chemicals, implant biomaterials, medicines and biofuels have been developed and are covered in this critical review. Companies have been estab...
متن کاملProcess Design and Evaluation of Biobased Polyhydroxyalkanoates (PHA) Production
Conventional plastic products are made of crude oil components through polymerization. Aim of the project ANIMPOL is to convert lipids into polyhydroxyalkanoates (PHA) which constitute a group of biobased and biodegradable polyesters. Replacing fossil based plastics with biobased alternatives can help reducing dependence on crude oil and decrease greenhouse gas emissions. As substrate material ...
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ژورنال
عنوان ژورنال: Synthetic and Systems Biotechnology
سال: 2017
ISSN: 2405-805X
DOI: 10.1016/j.synbio.2017.09.001